{"id":2,"date":"2015-05-13T19:00:12","date_gmt":"2015-05-13T18:00:12","guid":{"rendered":"https:\/\/www.umrs1176.universite-paris-saclay.fr\/?page_id=2"},"modified":"2026-10-12T15:16:08","modified_gmt":"2026-10-12T13:16:08","slug":"page-d-exemple","status":"publish","type":"page","link":"https:\/\/www.umrs1176.universite-paris-saclay.fr\/","title":{"rendered":"Accueil"},"content":{"rendered":"<p style=\"text-align: justify;\">L\u2019unit\u00e9 INSERM U1176, <strong>H\u00e9mostase Inflammation Thrombose,<\/strong> propose un projet int\u00e9gratif visant \u00e0 contribuer \u00e0 une meilleure connaissance des m\u00e9canismes fondamentaux gouvernant les \u00e9changes dynamiques entre le <span style=\"color: #ff0000;\">syst\u00e8me h\u00e9mostatique<\/span> et <span style=\"color: #ff0000;\">les cellules du compartiment vasculaire<\/span>, dans le but final de d\u00e9velopper des <span style=\"color: #0000ff;\">alternatives th\u00e9rapeutiques<\/span> dans le domaine de <span style=\"color: #0000ff;\">l\u2019h\u00e9mostase et de la thrombose.<\/span><\/p>\n<p data-start=\"77\" data-end=\"508\">L&rsquo;unit\u00e9 INSERM U1176\u00a0est dirig\u00e9e par\u00a0<a href=\"https:\/\/www.umrs1176.universite-paris-saclay.fr\/index.php\/organigramme\/\" target=\"_blank\">C\u00e9cile DENIS<\/a><\/p>\n<p><a href=\"https:\/\/www.umrs1176.universite-paris-saclay.fr\/wp-content\/uploads\/2023\/06\/U1176c2.jpg\"><br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2599 \" src=\"https:\/\/www.umrs1176.universite-paris-saclay.fr\/wp-content\/uploads\/2023\/06\/U1176c2-1024x512.jpg\" alt=\"Photo groupe Saint-Malo, CFH 2023\" width=\"718\" height=\"359\" srcset=\"https:\/\/www.umrs1176.universite-paris-saclay.fr\/wp-content\/uploads\/2023\/06\/U1176c2-1024x512.jpg 1024w, https:\/\/www.umrs1176.universite-paris-saclay.fr\/wp-content\/uploads\/2023\/06\/U1176c2-300x150.jpg 300w\" sizes=\"auto, (max-width: 718px) 100vw, 718px\" \/><\/a><\/p>\n<hr \/>\n<p style=\"text-align: center;\"><strong><span style=\"color: #0000ff;\">!!! NOUVELLES PUBLICATIONS !!!<\/span><\/strong><\/p>\n<ul>\n<li>\n<p class=\"heading-title\">Peyron et al, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40906928\/\" target=\"_blank\">Blood. 2025 Sep 4<\/a>\u00a0: A bispecific nanobody for the treatment of von Willebrand disease type 1<\/p>\n<\/li>\n<li>Solarz et al,\u00a0<a href=\"https:\/\/www.nature.com\/articles\/s41467-025-62487-2\" target=\"_blank\">Nature communications,\u00a02025 Aug 10<\/a>\u00a0: F-actin disassembly by the oxidoreductase MICAL1 promotes mechano-dependent VWF-GPIb\u03b1 interaction in platelets.<\/li>\n<\/ul>\n<ul>\n<li>Ang\u00e9nieux et al,\u00a0<a href=\"https:\/\/haematologica.org\/article\/view\/12157\" target=\"_blank\">Haematologica . 2025 Jul 3<\/a>\u00a0: Unveiling platelet aging with progressive \u03b2-galactose exposure as a signature of platelet senescence in humans and mice.<\/li>\n<\/ul>\n<ul>\n<li>Auditeau et al,\u00a0<a href=\"https:\/\/www-thieme-connect-com.proxy.insermbiblio.inist.fr\/products\/ejournals\/abstract\/10.1055\/a-2632-3001\" target=\"_blank\">Thromb Haemost. 2025 Jun 11<\/a>\u00a0: Implementing an assay detecting anti-drug antibody against emicizumab: experience from one center in France.<\/li>\n<\/ul>\n<ul>\n<li>Sefiane et al,<a href=\"https:\/\/haematologica.org\/article\/view\/12008\" target=\"_blank\">\u00a0Haematologica. 2025 Apr 3<\/a>\u00a0: Consistent clinical factor VIII equivalency is unlikely for non-factor therapies in hemophilic mice.<\/li>\n<\/ul>\n<ul>\n<li>Kauskot et al,\u00a0<a href=\"https:\/\/www-sciencedirect-com.proxy.insermbiblio.inist.fr\/science\/article\/pii\/S153878362500193X?via%3Dihub\" target=\"_blank\">J Thromb Haemost. 2025 Jun;23(6):2050-2059<\/a>\u00a0: Consensus protocol for platelet desialylation (\u03b2-galactose exposure) quantification using lectins by flow cytometry: communication from the ISTH SSC Subcommittee on Platelet Physiology.<\/li>\n<\/ul>\n<p style=\"text-align: center;\"><span style=\"color: #0000ff;\"><strong><a style=\"color: #0000ff;\" href=\"https:\/\/www.umrs1176.universite-paris-saclay.fr\/index.php\/publications-2025\/\" target=\"_blank\">&#8212; Liste des publications &#8212;<\/a><\/strong><\/span><\/p>\n<hr \/>\n<p>INSERM U1176<\/p>\n<p>CHU de Bic\u00eatre<br \/>\n80 rue du G\u00e9n\u00e9ral Leclerc<br \/>\nB\u00e2timent Gr\u00e9gory Pincus<br \/>\n94276 Le Kremlin Bic\u00eatre Cedex<\/p>\n<p>T\u00e9l : +33 (0)1 49 59 56 00<br \/>\nFax : +33 (0)1 46 71 94 72<\/p>\n<p>&nbsp;<\/p>\n<p>Si vous souhaitez faire un don : voici le lien\u00a0<a href=\"https:\/\/don.fondation-universite-paris-saclay.fr\/Hemostase\" target=\"_blank\">Don \u00e0 l&rsquo;unit\u00e9 U1176<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>L\u2019unit\u00e9 INSERM U1176, H\u00e9mostase Inflammation Thrombose, propose un projet int\u00e9gratif visant \u00e0 contribuer \u00e0 une meilleure connaissance des m\u00e9canismes fondamentaux gouvernant les \u00e9changes dynamiques entre le syst\u00e8me h\u00e9mostatique et les [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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